Reviewed by James Ives, M.Psych. (Editor) Axial spondyloarthritis (axSpA) is a chronic systemic rheumatoid-inflammatory disease associated with inflammation of the spine. “The affected patients often have been experiencing spinal pain since early adulthood”, EULAR President Professor Dr Iain B. McInnes, Director of the Institute of Infection, Immunity & Inflammation, The University of Glasgow, Scotland, explains:...
Tag: <span>Rheumatology</span>
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Moving the diagosis of rheumatic diseases into the era of precision medicine
by Delthia Ricks , Medical Xpress Many rheumatic conditions develop slowly and initially have inflammatory arthritis as the first sign that something is amiss. The trouble with such close similarity is the difficulty that clinicians have differentiating one condition from another in the early stages of the disease process. Dr. Rachel Knevel and colleagues at...
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The New JAK inhibitor Upadacitinib (Rinvoq) Shows Promise for Psoriatic Arthritis
Approved in 2019 for moderate to severe rheumatoid arthritis, the drug may offer an oral alternative to infused or injected biologics. The JAK inhibitor upadacitinib (Rinvoq) became a treatment option in 2019 for people with rheumatoid arthritis(RA) who had not responded well to methotrexate, the disease-modifying anti-rheumatic drug (DMARD) that is the first-line treatment for...
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Specially designed footwear reduces pain of knee osteoarthritis
by Boston University School of Medicine Wearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee osteoarthritis. Knee osteoarthritis affects approximately 275 million people worldwide and in 2017 was estimated to account for 8.3 million years lived with disability. Acetaminophen, non-steroidal anti-inflammatory drugs and opioids are most commonly...
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ACR releases gout management guideline
by American College of Rheumatology Today, the American College of Rheumatology (ACR) released the 2020 Guideline for the Management of Gout. The updated guideline reflects new clinical evidence that became available since the ACR last released a treatment guideline for the condition in 2012, Among the 42 recommendations offered, addressing standard treat-to-target urate lowering therapy...
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Vitamin D and Omega 3 supplements do not reduce risk of systemic inflammation
Results from VITAL study find that neither supplement taken over the course of a year was associated with a decrease in biomarkers of inflammation BRIGHAM AND WOMEN’S HOSPITAL Vitamin D and marine omega-3 fatty acids — also known as fish oil — are purported to have many health benefits, including reducing systemic inflammation. Signals of...
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Proving Painsomnia is Real: A Case Study
Living with Painsomnia It doesn’t matter if it is 11pm or 2am. Anyone seeking solidarity during a long night awake with pain can find a virtual friend on the Twitter #Painsomnia hashtag or by mentioning it on other tags frequented by people living with a chronic disease. Painsomnia is a patient-generated term for the vicious...
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Proving Painsomnia is Real: A Case Study
Living with Painsomnia It doesn’t matter if it is 11pm or 2am. Anyone seeking solidarity during a long night awake with pain can find a virtual friend on the Twitter #Painsomnia hashtag or by mentioning it on other tags frequented by people living with a chronic disease. Painsomnia is a patient-generated term for the vicious...
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Allopurinol dose escalation for gout doesn’t improve mortality
(HealthDay)—Allopurinol dose escalation is not associated with reductions in mortality risk among patients with gout, according to a study published in the August issue of Arthritis & Rheumatology. Brian W. Coburn, Ph.D., from the University of Nebraska Medical Center in Omaha, and colleagues assessed whether allopurinol dose escalation is associated with cause-specific mortality in patients with...
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Gene signatures and biomarkers predict onset of rheumatoid arthritis in at-risk individuals
The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) provide insight into molecular changes prior to the onset of arthritis which could inform future novel diagnostics and early therapeutic interventions. Rheumatoid arthritis (RA) is characterised by joint inflammation leading to destruction of bone and cartilage. Since structural joint damage is...
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