Tag: <span>Rifampin</span>

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New antibiotic effective against drug-resistant bacteria

First selective nucleoside-analog inhibitor of bacterial RNA polymerase Structure of bacterial RNA polymerase, showing the binding sites for the new antibiotic pseudouridimycin (PUM) and the current antibacterial drug rifampin (Rif). PUM has a lower resistance rate and a smaller resistance target than Rif — just 2 to 4 positions where alterations that result in PUM-resistance...