September 11, 2024 by Kendall Daniels, University of North Carolina at Chapel Hill School of Medicine The liver of miR-29TG and 2 year-old wildtype mice share changes in key aging-related genes and pathways. Credit: Communications Biology (2024). DOI: 10.1038/s42003-024-06735-zA team led by UNC School of Medicine researchers is the first to confirm that a small...
by Centro de Investigación Médica Aplicada (CIMA) Universidad de Navarra Replication stress induces lncRNAs associated to replicating chromatin. a (Top) Mechanism of action of hydroxyurea (HU) RNR: ribonucleotide reductase. (Bottom) Immunoblot analysis HCT116 cells treated with HU 1 mM for 8 h followed by 3 h recovery shows the reversible effect of HU on replication stress markers p-ATR,...
