by Bill Lubinger, Case Western Reserve University A hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). Note that this is a single strand of RNA that folds back upon itself. Credit: Vossman/ Wikipedia Irregularities in the body’s genetic coding to make proteins are linked to cancerous tumors. But most...
Reviewed by Emily Henderson, B.Sc. Jul 11 2022 For the function of many biomolecules, their three-dimensional structure is crucial. Researchers are therefore not only interested in the sequence of the individual building blocks of biomolecules, but also in their spatial structure. With the help of artificial intelligence (AI), bioinformaticians can already reliably predict the three-dimensional...
At any moment in the human body, in about 30 trillion cells, DNA is being “read” into molecules of messenger RNA, or mRNA, the intermediary step between DNA and proteins, in a process called transcription. Scientists have a good idea of how transcription gets started. Proteins called RNA polymerases are recruited to specific regions of...
Research suggests the products of transcription — RNA molecules — regulate their own production through a feedback loop. At any given moment in the human body, in about 30 trillion cells, DNA is being “read” into molecules of messenger RNA, the intermediary step between DNA and proteins, in a process called transcription. Scientists have a pretty...
New research shows that ultrasound could enhance the absorption of strands of RNA into colon cells in the gut, to block the production of proteins that promote inflammation. The study, performed in mice, could lead to improved treatments for gastrointestinal disorders such as inflammatory bowel disease. Researchers believe that their findings could lead to improved...
