Scientists investigate how the Cpeb4 protein mediates the production of osteoclasts, which are involved in bone and joint diseases, including osteoporosis.Peer-Reviewed Publication TOKYO UNIVERSITY OF SCIENCE A RECENT STUDY BY TUS RESEARCHERS REVEAL THAT THE CPEB4 PROTEIN MAY HAVE A ROLE IN REGULATING OSTEOCLAST DIFFERENTIATION. THIS, IN TURN, COULD LEAD TO THE DEVELOPMENT OF NEW...
by St. Jude Children’s Research Hospital Credit: Pixabay/CC0 Public DomainResearchers have puzzled over the neurodegenerative disorder Alzheimer’s disease for decades, but treatments to stop or reverse the disease’s effects on the brain have remained elusive. Scientists at St. Jude Children’s Research Hospital recently added an important piece to the puzzle by creating a mouse model...
by Children’s Hospital of Philadelphia A Wright’s stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0 Aberrant splicing of messenger RNAs encoding surface antigen CD22 leads to downregulation of this protein in pediatric B-lymphoblastic leukemia (B-ALL), rendering malignant cells resistant to the effects of CD22-directed immunotherapies, according...
by Jeffrey Norris, University of California, San Francisco Credit: NIH What kills most people who die from cancer is not the initial tumor. It’s the intolerable disease burden on the body that arises when tumor cells continually expand their numbers after spreading to different organs. In comparison to what is already known about specific mutations that...
