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Creating a new toehold for RNA therapeutics, cell therapies, and diagnostics
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Creating a new toehold for RNA therapeutics, cell therapies, and diagnostics

by  Harvard University Eukaryotic Toeholds (eToeholds) are engineered RNA-based control elements that, as in this example, can be specifically activated by viral “trigger RNAs” to enable synthesis of a reporter protein and thus signal the presence of the virus. I the future, eToeholds could be used to design safer and more specific RNA therapeutics, RNA diagnostics,...