MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MA — Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene. Their approach could make it possible to create targeted therapies for cancer and other diseases, by ensuring that synthetic genes are activated only in specific cells. The researchers demonstrated that...
Tag: <span>RNA therapies</span>
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Investigators discover new mechanism to boost RNA therapies
by Cedars-Sinai Medical Center A hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). Note that this is a single strand of RNA that folds back upon itself. Credit: Vossman/ Wikipedia Investigators from the Smidt Heart Institute at Cedars-Sinai have identified how biological pacemaker cells—cells that control your heartbeat—can “fight...