Tag: <span>RNA therapy</span>

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New method used to develop RNA therapy for the treatment of rare diseases
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New method used to develop RNA therapy for the treatment of rare diseases

by Justin Jackson, Medical Xpress Taxonomy of ASO-amenable variants. Two-step logic for classifying the amenability of genetic variants to splice modulation rescue (probably, possibly or unlikely). First, each variant is evaluated for its damaging impact on either canonical splicing or protein-coding function, on the basis of SpliceAI, MaxEntScan, LaBranchoR and REVEL. Second, each variant is...

RNA therapy for heart failure and organ fibrosis
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RNA therapy for heart failure and organ fibrosis

by Fraunhofer-Gesellschaft To better understand the molecular signaling pathways in healthy and diseased hearts, researchers are analyzing non-coding miRNA using real-time PCR. This can be used to identify disease-related miRNAs, such as miRNA 132. Credit: Fraunhofer-Gesellschaft RNA has already been making an impact in the context of the vaccine program, but the potential of RNA-based...