This news or article is intended for readers with certain scientific or professional knowledge in the field. Research produces dramatic results in laboratory studies involving fatal myelin disease that strikes children. A team led by Case Western Reserve University medical researchers has developed a potential treatment method for Pelizaeus-Merzbacher disease (PMD), a fatal neurological disorder...
Tag: <span>RNA</span>
Gut Piezo1 regulates gut and bone homeostasis via RNA sensing.
NATIONAL INSTITUTES OF NATURAL SCIENCES SCHEMATIC MODEL OF FECAL RNA-MEDIATED SEROTONIN PRODUCTION. view more CREDIT: KENTA MARUYAMA In a new study published in Cell, “RNA sensing by gut Piezo1 is essential for systemic serotonin synthesis”, a research team led by Kenta Maruyama M.D., Ph.D. from National Institute for Physiological Sciences (NIPS) explored the role of...
Researchers develop new approach to study the genetics of human disease
by Sheila Evans, University of Chicago Medical Center Many heritable immune diseases such as rheumatoid arthritis and blood-cell related traits derive from critical proteins not being made or not functioning correctly. But exactly how a person’s genes, the regulation of these genes and how the resulting proteins interact to cause disease is not widely understood....
Contrary to popular claim on social media, RNA vaccines do not alter our DNA
Inaccurate: RNA from a vaccine would not be able to directly alter our DNA, in part because of the chemical differences between the two nucleic acids. RNA also would not persist long enough to cause autoimmunity. Autoimmune diseases are chronic in nature, whereas RNA has a very short lifespan, being quickly degraded after it has...
Tiny mineral particles are better vehicles for promising gene therapy
UNIVERSITY OF WISCONSIN-MADISON MADISON, Wis. — University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination — including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans. The technology relies on inserting into...
Research team develops technology to improve effectiveness of stem cells in regenerative medicine
by The Spanish National Cancer Research Centre Stem cells have been holding great promise for regenerative medicine for years. In the last decade, several studies have shown that this type of cell, which in Spanish is called “mother cell” because of its ability to give rise to a variety of different cell types, can be...
NUS researchers uncover a novel protein which drives cancer progression
PRINT E-MAIL Cancers arise when the genetic code of normal cells is altered, causing excessive growth. Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have discovered a protein that drives the growth of cancers of the esophagus or liver by altering the genetic code in a...
New method developed for mapping brain areas according to molecular profile
by Felicia Lindberg, Karolinska Institutet Researchers have mapped the mouse brain into areas according to their molecular profile. In a new study researchers at Karolinska Institutet and KTH Royal Institute of Technology have developed a new kind of brain atlas based on an innovative method of mapping brain tissue into areas according to their molecular...
Scientists uncover new genetic mutations linked to autism spectrum disorder
by Sanford Burnham Prebys Medical Discovery Institute Scientists at Sanford Burnham Prebys Medical Discovery Institute and Radboud University Medical Center in the Netherlands have identified mutations in a gene called CNOT1 that affect brain development and impair memory and learning. The study is the first to link neurodevelopmental delays with CNOT1, suggesting that drugs that...
Experimental peptide targets Covid-19
Computational modeling yields a protein fragment that could bind to coronavirus spike proteins and destroy them. The research described in this article has been published on a preprint server but has not yet been peer-reviewed by scientific or medical experts. Using computational models of protein interactions, researchers at the MIT Media Lab and Center for...