Tag: <span>RNA</span>

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Gut Piezo1 regulates gut and bone homeostasis via RNA sensing.
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Gut Piezo1 regulates gut and bone homeostasis via RNA sensing.

NATIONAL INSTITUTES OF NATURAL SCIENCES SCHEMATIC MODEL OF FECAL RNA-MEDIATED SEROTONIN PRODUCTION. view more CREDIT: KENTA MARUYAMA In a new study published in Cell, “RNA sensing by gut Piezo1 is essential for systemic serotonin synthesis”, a research team led by Kenta Maruyama M.D., Ph.D. from National Institute for Physiological Sciences (NIPS) explored the role of...

Researchers develop new approach to study the genetics of human disease
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Researchers develop new approach to study the genetics of human disease

by Sheila Evans, University of Chicago Medical Center Many heritable immune diseases such as rheumatoid arthritis and blood-cell related traits derive from critical proteins not being made or not functioning correctly. But exactly how a person’s genes, the regulation of these genes and how the resulting proteins interact to cause disease is not widely understood....

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Tiny mineral particles are better vehicles for promising gene therapy

UNIVERSITY OF WISCONSIN-MADISON MADISON, Wis. — University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination — including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans. The technology relies on inserting into...

New method developed for mapping brain areas according to molecular profile
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New method developed for mapping brain areas according to molecular profile

by Felicia Lindberg, Karolinska Institutet Researchers have mapped the mouse brain into areas according to their molecular profile. In a new study researchers at Karolinska Institutet and KTH Royal Institute of Technology have developed a new kind of brain atlas based on an innovative method of mapping brain tissue into areas according to their molecular...

Scientists uncover new genetic mutations linked to autism spectrum disorder
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Scientists uncover new genetic mutations linked to autism spectrum disorder

by Sanford Burnham Prebys Medical Discovery Institute Scientists at Sanford Burnham Prebys Medical Discovery Institute and Radboud University Medical Center in the Netherlands have identified mutations in a gene called CNOT1 that affect brain development and impair memory and learning. The study is the first to link neurodevelopmental delays with CNOT1, suggesting that drugs that...

Experimental peptide targets Covid-19
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Experimental peptide targets Covid-19

Computational modeling yields a protein fragment that could bind to coronavirus spike proteins and destroy them. The research described in this article has been published on a preprint server but has not yet been peer-reviewed by scientific or medical experts. Using computational models of protein interactions, researchers at the MIT Media Lab and Center for...

Unexpected mental illnesses found in a spectrum of a rare genetic disorder
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Unexpected mental illnesses found in a spectrum of a rare genetic disorder

by UC Davis UC Davis MIND Institute researchers found an unexpected set of mental illnesses in patients with a spectrum of a rare genetic disorder. Their study revealed the need for clinicians to consider the complexities of co-existing conditions in patients with both psychological and fragile X associated disorders. Double-hit fragile X spectrum cases The...