RNA-targeting CRISPR reveals that hundreds of noncoding RNAs are essential—not “junk”—including in human development and cancerPeer-Reviewed Publication New York University Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes proteins; the function of...
Tag: <span>RNAs</span>
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Discovery of new step in how brain cells work could lead to new therapies for epilepsy
by RCSI University of Medicine Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy. This could lead to new treatment approaches for people with drug-resistant epilepsy. The study was led by researchers at FutureNeuro, the SFI Research Centre for Chronic and...
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Blood cells could serve as a ‘thermometer’ to detect breast cancer
by Maria Fernanda Ziegler, FAPESP Immune system cells in the blood of breast cancer patients undergo alterations early in the disease course, according to a study published in the journal Clinical & Translational Immunology. The authors believe that this discovery may contribute to the early identification of aggressive tumors and help enhance personalized immunotherapy strategies...
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The roles of RNA-RNA interactions
July 20, 2018, Ludwig Maximilian University of Munich Chronic regeneration of damaged endothelial cells at sites of disturbed blood flow in the vasculature promotes the development of atherosclerosis. Now an LMU team has further elucidated the role of a short RNA molecule in atherogenesis. Credit: Design-Cells / fotolia.com Atherosclerosis – the condition is popularly known as hardening...
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Researchers find hidden signals in RNAs that regulate protein synthesis
Study finds previously unknown strategy cells use to make protein CASE WESTERN RESERVE UNIVERSITY Scientists have long known that RNA encodes instructions to make proteins. The building blocks that comprise RNA–A, U, C, and Gs–form a blueprint for the protein-making machinery in cells. To make proteins, the machinery latches on RNA at one end and...