by King’s College London KCL-286 transcriptional neuronal signaling. KCL-286 binds to a retinoic acid receptor (RAR)β2/retinoid x receptor (RXR) heterodimer located at a retinoic acid response element (RARE). This results in activation of transcriptional pathways required for axonal regeneration. Credit: British Journal of Clinical Pharmacology (2023). DOI: 10.1111/bcp.15854 New orally available drug for spinal cord injury found to...
