A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports. Image: The new drug candidate, shown in green, fits precisely into the active site within the target protein, retonoid X receptor. Credit: Dipanjan Pan, University...
Tag: <span>sarcoma cell</span>
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Boosting sarcoma cell death
Ewing sarcomas – rare, aggressive childhood cancers – are derived from mesenchymal cells in bone and soft tissues, and children with metastatic disease have poor survival. In a search for new therapeutic options for Ewing sarcoma, Dai Chung, M.D., and colleagues tested a compound previously identified at Vanderbilt, ML327, that induces the expression of the cell...