NIH/NATIONAL INSTITUTE ON DRUG ABUSE Young men with cannabis (marijuana) use disorder have an increased risk of developing schizophrenia, according to a study led by researchers at the Mental Health Services in the Capital Region of Denmark and the National Institute on Drug Abuse (NIDA) at the National Institutes of Health. The study, published in Psychological Medicine, analyzed detailed...
Tag: <span>Schizophrenia</span>
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DNA methylation markers for increased risk of schizophrenia identified for first time in newborns
by Virginia Commonwealth University Credit: Pixabay/CC0 Public Domain An international research team led by investigators at Virginia Commonwealth University has identified for the first time markers that may indicate early in life if a person has susceptibility to schizophrenia. The ability to predict the risk of developing schizophrenia later in life may allow early detection and intervention, which...
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The antipsychotic clozapine linked to significantly less insomnia in people with schizophrenia
MEDICAL COLLEGE OF GEORGIA AT AUGUSTA UNIVERSITY IMAGE: DRS. BRIAN MILLER AND VAUGHN MCCALL CREDIT: AU PHOTOGRAPHER MICHAEL HOLAHAN. Insomnia affects up to half of people with schizophrenia and is thought to worsen the impact of their disease, including their risk of suicide. A new meta-analysis of the antipsychotics these patients take indicates those who...
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One-minute visual fixation can identify patients with schizophrenia
by Liu Jia, Chinese Academy of Sciences Credit: Pixabay/CC0 Public Domain In a study published online in the Schizophrenia Bulletin, researchers from Dr. Wang Wei’s lab at the Center for Excellence in Brain Science and Intelligence Technology of the Chinese Academy of Sciences, and Dr. Wang Jijun’ team at Shanghai Mental Health Center, Shanghai Jiao Tong University School of...
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Researchers discover age- and brain region–dependent expression of schizophrenia risk genes
by Justin Jackson, Medical Xpress Graphic summary of the study design. In this study, we evaluate four hypotheses: (i) Age-parsed networks in neurotypical brains explain more SCZ genetic risk than the same data not age-parsed. (ii) The course of SCZ enrichment differs between NCs and patients with SCZ. (iii) There is a molecular environment to...
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Vasodilator drug used in stroke patients found to reverse key symptoms of schizophrenia in mice
by Nagoya University Researchers used the drug fasudil to restore neurons and improve methamphetamine-induced cognitive dysfunction in a mouse model of schizophrenia. Credit: Rinako Tanaka, Department of Neuropsychopharmacology, Nagoya University Graduate School of Medicine A team from Nagoya University in Japan used the drug fasudil to reverse two common symptoms associated with schizophrenia: reduced density of...
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Potential therapeutic target for schizophrenia identified
by Melissa Rohman, Northwestern University Representative image of neuronal markers MAP2 (green) and Syn1 (magenta) stained in induced excitatory neurons. Credit: Euan Parnell, PhD. Targeting calcium signaling in neurons represents a promising therapeutic approach for treating a rare form of schizophrenia, according to a Northwestern Medicine study published in Biological Psychiatry. “This is the first time...
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Schizophrenia may be linked with vascular alterations in the brain, study suggests
Reviewed by Emily Henderson, B.Sc. Jan 19 2023 A study conducted in Brazil and reported in an article published in Molecular Psychiatry suggests that schizophrenia may be associated with alterations in the vascularization of certain brain regions. Researchers at the State University of Campinas (UNICAMP), D’Or Research and Education Institute (IDOR) and the Federal University of Rio de...
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Study examines brain aging in people with schizophrenia
by CORDIS Correlation coefficients of predicted brain age and FreeSurfer features across control and schizophrenia (SZ) groups. Bivariate correlations are shown to provide an indication of the relative contribution of features in brain age prediction. The figure shows Pearson correlations between predicted brain age and cortical thickness features (top row), cortical surface areas (middle row)...
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Scientists link rare genetic phenomenon to neuron function, schizophrenia
UNIVERSITY OF NORTH CAROLINA HEALTH CARE IMAGE: TANDEM REPEAT CREDIT: JIN SZATKIEWICZ LAB, UNC SCHOOL OF MEDICINE CHAPEL HILL, NC – In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides – the basic structural unit of...