by Yale School of Medicine Atopic dermatitis. Credit: AfroBrazilian/Wikimedia Commons, CC BY-SA Atopic dermatitis (AD) is a chronic, inflammatory skin disorder that has well-established associations with depression and anxiety. A new Yale School of Medicine study, published in Archives of Dermatological Research, finds AD is also associated with increased risk for schizophrenia and schizoaffective disorder. Schizophrenia is...
by Cell Press Schizophrenia-associated somatic copy number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions. Credit: Cell Genomics / Maury et al. As a psychiatric disorder with onset in adulthood, schizophrenia is thought to be triggered by some combination of environmental factors and genetics, although the exact cause is still not fully understood. In...
by David Mitchell, University of Georgia Clementz, McDowell and their teams have identified three new psychosis classifications using data captured from brain scans. Rather than grouping patients in the previous classifications of the DSM—schizophrenia, bipolar and schizoaffective disorder—they have established new groups called “biotypes.” Credit: Lindsay Bland Robinson Brett Clementz doesn’t love the term “schizophrenia.” Sure,...
by Leah Eisenstadt, Broad Institute of MIT and Harvard Protein changes at brain cell synapses from patients with schizophrenia were strikingly similar to those from patients with bipolar disorder. Credit: Sonja Vasiljeva/Broad Institute Although bipolar disorder and schizophrenia are diagnosed as distinct psychiatric conditions, both are considerably heritable with molecular roots that are poorly understood. Some...
NIH/NATIONAL INSTITUTE ON DRUG ABUSE Young men with cannabis (marijuana) use disorder have an increased risk of developing schizophrenia, according to a study led by researchers at the Mental Health Services in the Capital Region of Denmark and the National Institute on Drug Abuse (NIDA) at the National Institutes of Health. The study, published in Psychological Medicine, analyzed detailed...
by Virginia Commonwealth University Credit: Pixabay/CC0 Public Domain An international research team led by investigators at Virginia Commonwealth University has identified for the first time markers that may indicate early in life if a person has susceptibility to schizophrenia. The ability to predict the risk of developing schizophrenia later in life may allow early detection and intervention, which...
MEDICAL COLLEGE OF GEORGIA AT AUGUSTA UNIVERSITY IMAGE: DRS. BRIAN MILLER AND VAUGHN MCCALL CREDIT: AU PHOTOGRAPHER MICHAEL HOLAHAN. Insomnia affects up to half of people with schizophrenia and is thought to worsen the impact of their disease, including their risk of suicide. A new meta-analysis of the antipsychotics these patients take indicates those who...
by Liu Jia, Chinese Academy of Sciences Credit: Pixabay/CC0 Public Domain In a study published online in the Schizophrenia Bulletin, researchers from Dr. Wang Wei’s lab at the Center for Excellence in Brain Science and Intelligence Technology of the Chinese Academy of Sciences, and Dr. Wang Jijun’ team at Shanghai Mental Health Center, Shanghai Jiao Tong University School of...
by Justin Jackson, Medical Xpress Graphic summary of the study design. In this study, we evaluate four hypotheses: (i) Age-parsed networks in neurotypical brains explain more SCZ genetic risk than the same data not age-parsed. (ii) The course of SCZ enrichment differs between NCs and patients with SCZ. (iii) There is a molecular environment to...
by Nagoya University Researchers used the drug fasudil to restore neurons and improve methamphetamine-induced cognitive dysfunction in a mouse model of schizophrenia. Credit: Rinako Tanaka, Department of Neuropsychopharmacology, Nagoya University Graduate School of Medicine A team from Nagoya University in Japan used the drug fasudil to reverse two common symptoms associated with schizophrenia: reduced density of...
