by Indrani Mukherjee, Broad Institute of MIT and Harvard Morgan Sheng, core institute member and co-director of the Stanley Center for Psychiatric Research, is studying the function of genes linked to schizophrenia. Credit: Maria Nemchuk, Broad Communications Over the last 15 years, researchers at the Stanley Center for Psychiatric Research at the Broad Institute of...
by Jim Dryden, Washington University School of Medicine in St. Louis Distribution of p-WERCAP scores across the two youth cohorts. Figures depict the prevalences of different p-WERCAP score ranges. Cohort 1 participants completed WERCAP screens with 3-month and lifetime symptom timeframes (A). Cohort 2 participants completed WERCAP Screens with 3-month and 12-month symptom timeframes (B)....
Almost all family intervention models can prevent relapse in schizophrenia, according to a systematic review and meta-analysis published in the March issue of The Lancet Psychiatry. Alessandro Rodolico, M.D., from the University of Catania in Italy, and colleagues conducted a systematic review and network meta-analysis to examine family intervention models aimed at preventing relapse in patients with schizophrenia. Eleven family intervention models...
by University of Nottingham Credit: Pixabay/CC0 Public Domain New research has shown that over-activity in a specific area of the brain is linked to certain symptoms of schizophrenia, opening up possibilities for the development of more targeted treatments. Researchers from the University of Nottingham found that faulty inhibitory neurotransmission and abnormally increased activity in the...
by Karolinska Institutet Prevalence of common somatic and psychiatric comorbidities in individuals with schizophrenia and in the general population. Credit: https://openarchive.ki.se/xmlui/handle/10616/47823 Schizophrenia and eating disorders (EDs) are complex traits with considerable somatic and psychiatric morbidity, affecting 0.4–1% and 9% of the population, respectively. Risk for both is predominantly from genetic sources—64–81% for schizophrenia and 41–83% for...
by Weill Cornell Medical College Increasing levels of a potential disease factor results in additional brain cells (red) in a schizophrenia brain organoid. Credit: Dr. Michael Notaras. Multiple changes in brain cells during the first month of embryonic development may contribute to schizophrenia later in life, according to a new study by Weill Cornell Medicine...
by Wendy Bindeman , Vanderbilt University Credit: Pixabay/CC0 Public Domain A new study led by Jeff Conn, Lee E. Limbird Chair in Pharmacology, James Maksymetz, a former graduate student in the Conn laboratory, and other collaborators at the Warren Center for Neuroscience Drug Discovery has identified a protein in the central nervous system, known as...
by University of Surrey Typical rhythms of sleep, activity and light exposure. (a), (d): Light (yellow trace), activity (gray trace), 6-sulphatoxymelatonin (aMT6s) acrophase (red circles) and sleep timing (horizontal gray bars). (b) and (e): Average pattern of light exposure across the 24-h day. The shaded regions from white through to dark gray indicate the fraction of...
by Elsevier rsEEG results, DCM model structure, and rsEEG simulations. A – The mean normalized eyes closed and eyes open rsEEG power spectra (±s.e.m.) across all channels for Con (n=98; blue) and PScz (n=95; red) groups, divided into four frequency bands (dotted lines): θ (3-7 Hz), α (8-14 Hz), β (15-30 Hz) and γ (>31...
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE With the help of cutting-edge computer programs, researchers at the Icahn School of Medicine at Mount Sinai went through the genetic and medical records of more than 8,000 schizophrenia patients. They found that a tool commonly used in research for evaluating a person’s genetic risk...
