Psychiatrists have a dizzying array of diagnoses and not enough treatments. Hunting for the hidden biology underlying mental disorders could help. In 2018, psychiatrist Oleguer Plana-Ripoll was wrestling with a puzzling fact about mental disorders. He knew that many individuals have multiple conditions — anxiety and depression, say, or schizophrenia and bipolar disorder. He wanted...
by RIKEN Levels of the sphingolipid S1P were lower than normal in the corpus callosum (white matter) in the postmortem brains of people with schizophrenia. Credit: RIKEN Researchers at the RIKEN Center for Brian Science (CBS) in Japan have discovered a deficiency in the brains of people with schizophrenia that could lead to the development...
By : Rich Haridy A newly published article in the New England Journal of Medicine is reporting the successful results of a clinical trial testing an experimental drug designed to treat psychosis in schizophrenia. The drug works unlike any other existing anti-psychotic medication, and without many of their negative side effects. The development of anti-psychotic...
Provides clearest picture yet of the 22q syndrome brain UNIVERSITY OF SOUTHERN CALIFORNIA What if the key to a better understanding of schizophrenia has been here all along–but researchers haven’t had the resources to study it? Now, thanks to the pooled data and insights from researchers around the world, USC researchers have the clearest picture...
by Allyson Mann, University of Georgia Research by a University of Georgia psychologist shows that targeting one particular symptom of schizophrenia has a positive effect on other symptoms, offering significant promise for treating an aspect of schizophrenia that currently has no pharmaceutical options. A team led by Gregory Strauss published a study confirming that successfully...
Researchers at Karolinska Institutet and their colleagues in Germany, the USA and Finland have studied the safety of very long-term antipsychotic therapy for schizophrenia. According to the study, which is published in the scientific journal World Psychiatry, mortality was higher during periods when patients were not on medication than when they were. People with schizophrenia...
by University of Toronto Four unsolved mysteries around schizophrenia have long plagued the medical community, but a new hypothesis identifying a common link between them and an almost forgotten epidemic of a disease called pellagra could have profound implications for our understanding of psychosis in poorer nations. The new hypothesis has implications for how a subgroup...
RIKEN Working with model mice, post-mortem human brains, and people with schizophrenia, researchers at the RIKEN Center for Brain Science in Japan have discovered that a subtype of schizophrenia is related to abnormally high levels hydrogen sulfide in the brain. Experiments showed that this abnormality likely results from a DNA-modifying reaction during development that lasts throughout life. In addition to...
Posted Today Schizophrenia affects more than 21 million people worldwide. It is a mental disorder, characterized by a decreased ability to understand reality. People with this condition suffer from unclear or confused thinking, hearing voices, violent thoughts and other symptoms. Men are affected more often than women, which is why scientists set out looking for...
An 18-year joint Australian-Indian study made possible by the recruitment, diagnosis and DNA screening of thousands of people in India has identified a new clue in the quest for causes of schizophrenia and potential treatments. A collaboration between The University of Queensland and a team of Indian researchers led by Professor Rangaswamy Thara, co- founder and director of the Schizophrenia Research Foundation...
