Peer-Reviewed Publication UNIVERSITY OF VIRGINIA HEALTH SYSTEM “NOW THAT WE ARE BEGINNING TO UNDERSTAND HOW THIS INFLAMMATION STARTS, WE MIGHT BE ABLE TO PREVENT THIS PROCESS, WITH THE ULTIMATE GOAL OF LIMITING INFLAMMATION AND TREATING DISEASE,” SAID RESEARCHER LAURA E. NEWMAN, PHD.CREDIT: COURTESY NEWMAN LAB Researchers have discovered how “leaky” mitochondria – the powerhouses of...
by Salk Institute Human astrocytes (green) extending processes that wrap around the host blood vessel (magenta). Credit: Salk InstituteThe brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain. The other half—roughly 85 billion cells—are non-neuronal cells called glia. The most common...
by Technical University of Denmark Combined specificity tree for HLA-DR, HLA-DP, and HLA-DQ. Orange molecules have peptide coverage corresponding to at least 50 high-confidence ligands, and blue molecules have a pseudo-sequence distance of at most 0.05 to an orange molecule. Logos in red frames correspond to noncovered molecules. Credit: Jonas Birkelund Nilsson A new paper in...
Are we on the brink of a cure for heart disease? That was the question being whispered by normally cautious cardiologists at the American Heart Association annual conference in Philadelphia last week. Over three packed days, a raft of game-changing scientific discoveries have been unveiled by the world’s leading specialists – many of which will...
HARVARD MEDICAL SCHOOL At a glance: Scientists have discovered a previously unknown mechanism by which cells break down proteins that are no longer needed.These proteins are short-lived and modulate genes that support important neural, immune, and developmental processes.The mechanism could inform the design of therapies to treat conditions that arise when cells make too much...
According to researchers at Tel Aviv University (TAU), this new model could help with personalized early detection for breast cancer. By JUDY SIEGEL-ITZKOVICH Published: AUGUST 16, 2023 16:47Updated: AUGUST 16, 2023 16:48 A 3D rendering of cancer cells (Illustrative).(photo credit: INGIMAGE)Advertisement Every case of breast cancer in women (and a minority of men) is somewhat different. A new model developed in...
HEALTH31 July 2023 By DAVID NIELD Killer T cells surround a cancer cell. (NIH Image Gallery/Flickr/Public Domain) One of the challenges in treating cancer is stopping it from metastasizing, and a new study reveals one of the fundamental mechanisms through which this happens. Now we know about this mechanism, perhaps we can stop it. Key to this newly...
By UNIVERSITY OF HELSINKI JUNE 26, 2023 Dementia, a prevalent and distressing neurodegenerative disorder, exerts its grip on countless individuals across the globe. This condition manifests through a progressive decline in cognitive functions, including memory impairment and the inability to carry out routine activities. As the disease advances, individuals grappling with dementia encounter substantial challenges in communication,...
by the University of Montreal Arhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (± SEM) of Arhgef7 and Dcc in dissociated commissural neurons (n = 3). (B) Dissociated commissural neurons were fixed and immunostained for Arhgef7 and Dcc. Scale bar,...
Scientists have developed a specially engineered biochip that uses electricity to heal wounds up to three times faster than normal. It’s well known that electric fields can guide the movements of skin cells, nudging them towards the site of an injury for instance. In fact, the human body generates an electric field that does this naturally. So...
