by Cincinnati Children’s Hospital Medical Center A microscopic photo of a blood smear from a transgenic mouse that mimics the human immune disorder, secondary HLH (hemophagocytic lymphohistiocytosis). The image shows macrophage immune cells (indicated by arrow) flooding healthy tissue cells during a cytokine storm caused by HLH in a very similar fashion t what occurs...
Tag: <span>scientists</span>
The science of the penny dropping: Scientists discover memory recall and formation happens at specific times ‘due to the oscillation of brainwaves’
By JOE PINKSTONE FOR MAILONLINE Memory formation and recall is linked to specific brainwaves called theta waves These fire three times a second and only when a person learns successfully They originate from the hippocampus region, deep inside a person’s brain They are again produced when a person remembers one of their memories Recall is...
First map of proinsulin’s ‘social network’ reveals new drug target for type 2 diabetes
Study reveals previously unknown protein that helps proinsulin fold and opens new avenues for diabetes research SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE Scientists at Sanford Burnham Prebys Medical Discovery Institute have mapped for the first time the vast network of proteins that interact with proinsulin, the protein the body normally processes into insulin. The study,...
Exploiting viruses to attack cancer cells
An adenovirus is now better able to target and kill cancer cells due to the addition of an RNA stabilizing element. Hokkaido University scientists have made an adenovirus that specifically replicates inside and kills cancer cells by employing special RNA-stabilizing elements. The details of the research were published in the journal Cancers. Much research in...
Antibody neutralizes SARS and COVID-19 coronaviruses
The neutralizing antibody, called S309, is on an accelerated path toward clinical trials. An antibody first identified in a blood sample from a patient who recovered from Severe Acute Respiratory Syndrome in 2003 inhibits related coronaviruses, including the cause of COVID-19. The antibody, called S309, is now on a fast-track development and testing path at...
Genome-wide pattern found in tumors from brain cancer patients predicts life expectancy
by University of Utah Health Sciences In her Genomic Signal Processing Lab, Alter develops new mathematical methods that are uniquely suited for personalized medicine. Credit: Nathan L. Galli, University of Utah For the past 70 years, the best indicator of life expectancy for a patient with glioblastoma (GBM)—the most common and the most aggressive brain...
Scientists Found A Way to Disable a Gene Responsible For Obesity: Worry About Getting Too Fat No More?
Scientists were able to prevent obesity in mice by blocking macrohages, key inflammatory cells, within the body. Researchers from the Washington University School of Medicine in St. Louis have successfully disabled a gene in specific mouse cells, preventing mice from becoming obese even after being fed a high-fat diet. Macrophages, vital inflammatory cells which are...
Scientists edge closer to treatment for myotonic dystrophy
by University of Nottingham untreated and treated with kinase inhibitors. Following treatment with inhibitors targeting CDK12 nuclear foci in DM1 cells are reduced. Credit: Dr. Ami Ketley , the University of Nottingham Scientists at the University of Nottingham have taken a step closer towards developing a treatment for the long-term genetic disorder, myotonic dystrophy. In...
Scientists discover a novel neuroimmune pathway
by ShanghaiTech University Research carried out collaboratively by Professors Qi Hai and Zhong Yi from Tsinghua University and Professor Hu Ji from the School of Life Science and Technology (SLST) of ShanghaiTech University was published in a Nature article titled “Brain control of humoral immune responses amenable to behavioral modulation.” The researchers identify a specific...
New mask material can remove virus-size nanoparticles
Scientists around the world are scrambling to adapt their research to find solutions to the many problems raised by the Covid-19 pandemic sweeping the world, not the least being a face mask shortage. “We have developed and tested a highly breathable nanocellulose material that can remove particles smaller than 100 nanometres, the size of viruses,”...