Tag: <span>Senescent Cell</span>

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Chemotherapy becomes more efficient when senescent cells are eliminated by immunotherapy, shows study
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Chemotherapy becomes more efficient when senescent cells are eliminated by immunotherapy, shows study

by Institute for Research in Biomedicine (IRB Barcelona) Senescent human melanoma tumor cells. In brown, the PD-L2 protein acts as a protective shield and prevents the action of the immune system. Credit: IRB BarcelonaCancer treatments, including chemotherapy, in addition to killing a large number of tumor cells, also result in the generation of senescent tumor cells...

MYSM1 Overexpression Extends Life in Mice via a Reduced Senescent Cell Burden
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MYSM1 Overexpression Extends Life in Mice via a Reduced Senescent Cell Burden

Senescent cell accumulation is an important cause of degenerative aging. Senescent cells cease replication and begin to secrete an inflammatory mix of signals that disrupt tissue structure and function. These cells are created constantly, largely as a result of somatic cells hitting the Hayflick limit on cellular replication, but also as a result of injury,...