by Chen Na, Chinese Academy of Sciences The intracellular mechanisms that support Rutin to function as a novel senomorphic agent in antiaging interventions. Credit: Dr. SUN’s group Since the discovery of hallmark features of senescence such as cell cycle arrest, apoptosis resistance and development of a senescence-associated secretory phenotype (SASP), efforts in understanding how senescent cells...
Tag: <span>Senomorphic</span>
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An Example of Senomorphic Drug Discovery
Senescent cell accumulation is a feature of aging, a growing imbalance between the rate of creation and rate of destruction. Senescent cells perform a number of useful tasks in the short-term, but when present for the long-term, their inflammatory secretions disrupt tissue function and contribute meaningfully to the onset and progression of age-related disease. A great many research...