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The absence of a single mitochondrial protein causes severe inflammation

A study performed at IRB Barcelona supports the notion that mitochondrial defects underlie a set of diseases of unknown origin that involve chronic muscle inflammation IMAGE: MITOCHONDRIAL DNA STRESS (IN RED) TRIGGERS THE INFLAMMATORY RESPONSE IN MOUSE MUSCLE CELLS DEVOID OF OPA1 (NUCLEI IN GREEN).  CREDIT: AIDA RODRÍGUEZ, IRB BARCELONA The link between mitochondria and inflammation...

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The absence of a single mitochondrial protein causes severe inflammation

The link between mitochondria and inflammation is still unclear. But it is known is that, for example, the accumulation of defective mitochondria, which should have been removed, causes inflammation. Scientists at the Institute for Research in Biomedicine (IRB Barcelona) headed by Antonio Zorzano, also full professor of the University of Barcelona and researcher in the...