Tag: <span>Sex-specific difference</span>

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Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer’s disease progression
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Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer’s disease progression

by Texas Children’s Hospital The top 98 EAML genes are connected to GWAS genes, dysregulated in AD patients, and capable of separating AD and healthy control samples. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-38374-z Alzheimer’s disease (AD) is a complex neurodegenerative illness with genetic and environmental origins. Females experience faster cognitive decline and cerebral atrophy than males, while males...

Sex-specific differences seen in response to reduced insulin activity
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Sex-specific differences seen in response to reduced insulin activity

by Max Planck Society Neurons (green) in the male brain react differently to lowered insulin signaling. Credit: M. Baghdadi, Max Planck Institute for Biology of Ageing Insulin is not only a regulator of blood sugar, but also has an influence on life expectancy. If the insulin signaling pathway is inhibited, animals live longer. But which...