by University of California, Irvine Cannabis appears to be a safe and potentially effective treatment for the chronic pain that afflicts people with sickle cell disease, according to a new clinical trial co-led by University of California, Irvine researcher Kalpna Gupta and Dr. Donald Abrams of UC San Francisco. The findings appear in JAMA Network...
While the world worries about novel coronavirus SARS-CoV-2, other viruses continue to be used for the good – as vectors that ferry in healing genes for gene therapy and editing. Charles Hough calls himself “reborn” after lentiviruses – disabled versions of HIV – gave his blood cells the gene that overrides the mutant one that...
‘Forward-oriented’ design might boost treatment effectiveness and broaden use NIH/NATIONAL HEART, LUNG AND BLOOD INSTITUTE Researchers at the National Institutes of Health (NIH) have developed a new and improved viral vector–a virus-based vehicle that delivers therapeutic genes–for use in gene therapy for sickle cell disease. In advanced lab tests using animal models, the new vector was up to 10 times more efficient at incorporating corrective genes into bone marrow stem...
Is gene therapy the answer to sickle cell disease? An experimental treatment that promises to correct the condition at the genetic level has already shown great promise in a clinical trial. Researchers reported that a patient who has gone through gene therapy to cure sickle cell disease no longer experiences symptoms and has an increased...
