September 12, 2024 by NIH/National Human Genome Research Institute NIH researchers and collaborators have found that being a carrier for sickle cell disease, known as having sickle cell trait, increases the risk of blood clots, a risk that is the same among diverse human populations that may not traditionally be associated with sickle cell disease....
July 19, 2018, Children’s Hospital of Philadelphia Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease (SCD). Experiments in cultured human cells reveal that blocking the protein reduces the characteristic sickling that distorts the...
The test and the traitA new study in JAMA finds that HbA1c tests underreport a key blood sugar measure in African Americans with sickle cell trait. A routine diabetes test produces lower blood sugar readings in African-Americans with sickle cell trait than in those without, potentially leading patients to remain untreated or with a mistaken...
