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Key signaling protein identified as possible target for new therapies in hard-to-treat cancers
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Key signaling protein identified as possible target for new therapies in hard-to-treat cancers

by American Physiological Society Credit: Function (2023). DOI: 10.1093/function/zqad053The unique signaling protein known as TRPM7 can stimulate and interact with an important cellular signaling hub called the AKT machinery, which is a well-known component of multiple cellular functions that drive growth and proliferation. This interaction causes a significant increase in the gene expression of COX-2, an...