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Using CRISPR-interference and single-cell transcriptomics to systematically examine inflammatory reactive states
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Using CRISPR-interference and single-cell transcriptomics to systematically examine inflammatory reactive states

by Ingrid Fadelli, Medical Xpress GFAP immunostaining of an iPSC-derived astrocyte displaying a stellate ramified morphology in co-culture with iPSC-derived neurons (not visualized). Credit: Leng et al. Astrocytes or astroglia, the largest glial cell population in the central nervous system (CNS), perform numerous vital functions. Among other things, these glial cells (i.e., cells supporting functions...