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Powering the brain: How energy is distributed within single cells
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Powering the brain: How energy is distributed within single cells

by Bill Hathaway, Yale University Using a novel biosensor known as HYlight — a fluorescent imaging technology — researchers were able to monitor and map metabolic activity within individual neurons of C. elegans (a type of nematode worm) over time and under different conditions. Credit: Proceedings of the National Academy of Sciences (2024). DOI: 10.1073/pnas.2314699121Every system...

Technique allows mapping of epigenetic information in single cells at scale
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Technique allows mapping of epigenetic information in single cells at scale

Histones are tiny proteins that bind to DNA and hold information that can help turn on or off individual genes. Researchers at Karolinska Institutet have developed a technique that makes it possible to examine how different versions of histones bind to the genome in tens of thousands of individual cells simultaneously. The technique was applied to the...