Sirtuins are connected to the upregulation of cellular stress response mechanisms triggered by, for example, calorie restriction. Given the failure of past attempts to intervene in aging at the point of sirtuin 1, it may be that the influence of sirtuins on the pace of aging simply isn’t large enough to be useful. That said, work on other sirtuins, such as...
Tag: <span>Sirtuins</span>
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New mechanism activates bone-building cells in Osteoperosis
The number of osteoporosis medications that promote bone formation is few compared to those that suppress bone resorption. A research group led by Kumamoto University scientists has discovered that the gene SIRT7 is important for bone formation, and has discovered a new mechanism to activate gene functions essential for bone formation. The researchers believe that the SIRT7-regulated osteoblastogenesis...