9 January 2023 Representative images of a WM983B melanoma cell nucleus with a nuclear envelope bleb stained for Lamin A/C (green), Lamin B1 (magenta) and DNA (blue). Scale bar, 10 μm The study, published today in Nature Cell Biology, modelled the behaviour of aggressive melanoma cells that are able to change the shape of their nucleus to...
SHIBAURA INSTITUTE OF TECHNOLOGY IMAGE: THE RISK OF CANCER ASSOCIATED WITH LONG-TERM EXPOSURE TO ARSENIC IN DRINKING WATER CAN BE MITIGATED THROUGH REGULAR TREATMENT WITH CALCITRIOL, AN ACTIVATED FORM OF VITAMIN D3. CREDIT: ICHIRO YAJIMA FROM SIT, JAPAN According to recent estimates, over 140 million people from 50 countries regularly get exposed to arsenic through...
by The Associated Press A sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a potential skin cancer vaccine they are developing using the same technology behind COVID-19 preventive shots did well in...
by Wiley Credit: CC0 Public Domain Numerous studies have shown that drugs called immune checkpoint inhibitors can boost the immune system’s response against various cancers. Now a phase II clinical trial has demonstrated that patients with a serious form of skin cancer called advanced cutaneous squamous cell carcinoma can benefit from the immune checkpoint inhibitor...
Researchers from the University of Helsinki, HUS Comprehensive Cancer Center, Aalto University and Stanford University have developed an artificial intelligence model that predicts which skin cancer patients will benefit from a treatment that activates the immune defence system. In practice, the AI model makes it possible to diagnose skin cancer with a blood test, determine the prognosis...
by Boston University BRAFV600E activates the Hippo tumor-suppressor pathway. a Representative immunoblot (IB) of dox-inducible BRAFV600E Mel-ST cells cultured ± dox for 24 h. b IB of two different dox-inducible BRAFV600E Mel-ST clones cultured ± dox for 24 h (n ≥ 4 independent experiments, graph shows mean relative intensity ± SEM, two-tailed unpaired t test). c Left, IB of two dox-inducible BRAFV600E Mel-ST clones cultured...
by Katie Lee, Erin McMeniman and H. Peter Soyer, The Conversation Credit: Shutterstock Two in three Australians will have a skin cancer in their lifetime, nearly all of them basal cell carcinomas (BCC), squamous cell carcinomas (SCC) or melanomas. If the spot removed was more like a sore or lump than a mole, it’s likely your...
by Columbia University Irving Medical Center Credit: Unsplash/CC0 Public Domain Dark skin does provide some protection against the sun’s ultraviolet rays, but it’s a myth that people with dark skin tones are immune to the harmful effects of UV radiation. People of color have a lower risk of developing skin cancer than people with fair...
UNIVERSITY OF WASHINGTON As the most serious type of skin cancer, a melanoma diagnosis carries emotional, financial and medical consequences. That’s why recent studies finding that there is an overdiagnosis of melanoma are a significant cause for concern. “Overdiagnosis is the diagnosis of disease that will not harm a person in their lifetime. If melanoma...
When Hispanic people get a skin cancer diagnosis, their tumors are about 17% larger than those of white people, researchers say. According to the American Academy of Dermatology (AAD), skin cancer is often diagnosed at a more advanced stage in people with black and brown skin, leading to worse results. This makes it especially important to know the signs...
