Melanoma patients with a history of smoking cigarettes are 40 per cent less likely to survive their skin cancer than people who have never smoked, according to a new report funded by Cancer Research UK. AzerTAc The study of more than 700 melanoma patients mainly from the north of England – and published today in...
Tag: <span>skin cancer</span>
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Skin cancer can spread in mice by hijacking the immune system
Targeting these molecules with inhibiting drugs could help to prevent this aggressive skin cancercoming back after treatment. Credit: CC0 Public Domain Scientists have uncovered molecules released by invasive skin cancer that reprogram healthy immune cells to help the cancer to spread. The findings of the Cancer Research UK-funded study are published in Cell, today. Researchers...
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Unraveling the genetic causes of skin cancer
New research from American University shows interplay between key gene and receptor AMERICAN UNIVERSITY Skin cancer is on the rise in the United States. Squamous cell carcinoma, the second most common form of cancer in the U.S., has the highest mortality rate of all non-melanoma skin cancers. In roughly two to five percent of patients, the disease will metastasize and spread...
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Visual inspection alone is insufficient to diagnose skin cancer
The review, which has recently been published in The Cochrane Library, summarises a large body of research looking at the accuracy of tests in supporting decision making in skin cancer diagnosis. The early and accurate detection of all types of skin cancer is essential to managing the disease and to improving survival rates in melanoma,...
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Larotrectinib: Targeting DNA in cancer therapy
While other toddlers her age were fighting naptime, two-year-old Michelle was battling an aggressive, life-threatening cancer. Doctors at Children’s Hospital Los Angeles saved her life in an epic battle, wielding what is being hailed as a “magic bullet” in the fight against certain cancers. Michelle, 2, participated in the clinical trial for larotrectinib at Children’s Hospital Los...
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A team of scholars tested a new way of skin cancer early diagnostics
The methods created by the team, allowed to increase the efficiency of diagnosis up to 97 percent SAMARA UNIVERSITY A team of scholars of Samara National Research University and Samara State Medical University, as well as clinic specialists of Samara Regional Oncology Centre (SROC), tested a new way of skin cancer early diagnostics with the help of original complex of three devices. The efficiency of oncology treatment is directly connected...
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Scientists uncover why very few of the many mutated cells in our skin go on to eventually form cancer
Normal skin contains a patchwork of mutated cells, yet very few go on to eventually form cancer and scientists have now uncovered the reason why. Researchers at the Wellcome Sanger Institute and MRC Cancer Unit, University of Cambridge genetically engineered mice to show that mutant cells in skin tissue compete with each other, with only...
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Researchers reveal cause of aggressive skin cancer in patients with butterfly syndrome
The insights could open the door to a more effective treatment approach for patients with rare disorder THOMAS JEFFERSON UNIVERSITY PHILADELPHIA) – Patients with a rare skin disease, commonly called Butterfly Syndrome, that causes chronic blistering and extensive scarring also develop an aggressive and fatal form of cancer early in life. Now an international team...
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APOBEC-Linked Mutational Signatures Drive Skin Cancer in Recessive Dystrophic Epidermolysis Bullosa
NEW YORK (GenomeWeb) – Mutational signatures linked to the APOBEC family drive the development of early-onset squamous cell carcinomas of the skin among individuals with a rare genetic disorder condition. Recessive dystrophic epidermolysis bullosa (RDEB) is a rare genetic disorder caused by COL7A1 mutations that lead to skin fragility, tissue damage, and inflammation. Wounds that...
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Common skin cancer can signal increased risk of other cancers, Stanford researchers say
People who develop abnormally frequent cases of a skin cancer known as basal cell carcinoma appear to be at significantly increased risk for the development of other cancers, including blood, breast, colon and prostate cancers, according to a preliminary study by researchers at the Stanford University School of Medicine. The increased susceptibility is likely caused...