JANUARY 11, 2022 by Center for Genomic Regulation A keratinocyte undergoing cell division surrounded by senescent keratinocytes. The overall size of the cells and their nucleus are a typical characteristic of senescence, which play an important role in tumour suppression. Credit: Annagiulia Ciocia/CRG A study published today in Cell Reports reveals important insights into the molecular mechanisms...
by Peter Grad , Medical Xpress “This paper made my jaw drop.” “It is just a wacko hypothesis.” “This article isn’t so much a scientific paper as a representation of what a moron thinks a scientific paper is.” “You haven’t seen the stupidest published SARS-CoV-2 take yet [until you read this]. I PROMISE you.” The...
ROCKEFELLER UNIVERSITY Skin is our body’s most ardent defender against pathogens and other external threats. Its outermost layer is maintained through a remarkable transformation in which skin cells swiftly convert into squames–flat, dead cells that provide a tight seal between the living portion of the skin and the world outside. “Throughout our lifetime, squames are...
Skin grafts are risky in an increasing number of patients, partly due to rising rates of diabetes This method by the Salk Institute could avoid dangerous outcomes UC San Diego biology professor Juan Carlos Izpisua Belmonte explains his work People with severe burns, bedsores or chronic diseases such as diabetes are at risk for developing...
Researchers transform mature cells from the brain, heart and more into skin cells A new study published in Nature Communicationsreveals that it is possible to repurpose the function of different mature cells across the body — and harvest new tissue and organs from these cells. The research tracks the transformation of genetically manipulated cells into melanocytes,...
Stem cells are the blank slate on which all the specialized cells in our bodies are built, and finding ways to revert adult cells back to that stage can help fight a whole range of illnesses. A breakthrough came about 10 years ago when researchers discovered that skin cells could be “reprogrammed” into stem cells...
Researchers at the University of Bergen have transformed skin puncture cells from diabetes patients into insulin producing cells, using stem cell techniques. The researchers’ aim is to transplant these cells under the skin of people with diabetes. “This study is a step towards discovering how “stand-in” cells can secrete insulin in the body,” says Professor...
Researchers from the University of Illinois at Chicago have identified a molecular switch that converts skin cells into cells that make up blood vessels, which could ultimately be used to repair damaged vessels in patients with heart disease or to engineer new vasculature in the lab. The technique, which boosts levels of an enzyme that keeps...
Research team led by Milica Radisic uses their patented peptide to close non-healing chronic wounds caused by diabetes Summary: Scientist have demonstrated for the first time that their peptide-hydrogel biomaterial prompts skin cells to ‘crawl’ toward one another, closing chronic, non-healing wounds often associated with diabetes, such as bed sores and foot ulcers. Time may...
