September 23, 2024 by University of Dundee Credit: Unsplash/CC0 Public DomainExperts from the University of of Dundee’s Centre for Targeted Protein Degradation (CeTPD), working with Boehringer Ingelheim scientists, have developed a breakthrough small-molecule drug, a “protein degrader.” KRAS is the most mutated gene in cancer with mutations occurring in 17%–25% of all cancers, affecting millions...
by University of California – San Diego A colorized scanning electron micrograph depicts human red blood cells. Credit: UC San Diego Health Sciences Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an...
by University of California, San Francisco Credit: Unsplash/CC0 Public Domain A small molecule called ISRIB that was identified at UC San Francisco can reverse the neuronal and cognitive effects of concussion in mice weeks after an injury occurred, new research has found. ISRIB blocks the integrated stress response (ISR), a quality control process for protein...
