Tag: <span>SMARt-420</span>

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Old target, new mechanism for overcoming tuberculosis resistance

In strains of tuberculosis that have developed drug resistance mutations, researchers have identified a secondary pathway that can be activated to reinstate drug sensitivity. The rise of drug-resistant tuberculosis poses a serious threat to humans, with approximately 580,000 cases occurring in 2015, resulting in about 250,000 deaths. Current treatments against the tuberculosis-causing bacteria include prodrugs,...