Written by Samantha C. Shapiro, MD | Reviewed by Mandy Armitage, MD Published on November 11, 2022 Key takeaways: Urine (pee) is made up of water and waste. Pee smells different when there’s less water and/or more waste. Certain foods, medications, and dehydration can cause smelly pee. Less commonly, smelly pee might be due to...