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CAR macrophages go beyond T cells to fight solid tumors
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CAR macrophages go beyond T cells to fight solid tumors

by Perelman School of Medicine at the University of Pennsylvania Chimeric antigen receptor (CAR) T cell therapy has been a game-changer for blood cancers but has faced challenges in targeting solid tumors. Now researchers from the Perelman School of Medicine at the University of Pennsylvania may have an alternative to T cell therapy that can...

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Researchers engineer macrophages to engulf cancer cells in solid tumors

One reason cancer is so difficult to treat is that it avoids detection by the body. Agents of the immune system are constantly checking the surfaces of cells for chemical signals that say they belong, but cancer cells express the same chemical signals as healthy ones. Without a way for the immune system to tell...

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