Tag: <span>SREBPs</span>

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Vitamin D discovery could prove key to new treatments for metabolic disorders and certain cancers

A team led by Motonari Uesugi, professor and deputy director of Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS), found that a vitamin D metabolite known as ’25-OHD’ inhibits proteins that regulate lipid production. Those proteins, called sterol regulatory element-binding proteins (SREBPs), cannot then stimulate expression of lipid-producing genes. “To our knowledge, this is the...