LEIBNIZ-FORSCHUNGSINSTITUT FÜR MOLEKULARE PHARMAKOLOGIE IMAGE: IN FED CELLS, EARLY ENDOSOMES FORM CONTACTS WITH ER TUBULES. TUBULAR ER MEMBRANES FACILITATE MITOCHONDRIAL FISSION AND SERVE AS SOURCE FOR LIPID DROPLET FORMATION. NUTRIENT STARVATION-INDUCED HYDROLYSIS OF ENDOSOMAL PI(3)P BY MTM1 REDUCES MEMBRANE CONTACTS BETWEEN THE TUBULAR ER AND EARLY ENDOSOMES. THE RESULTING LOSS OF PERIPHERAL ER TUBULES INDUCES...
When the slime mold Dictyostelium discoideum, or Dicty for short, runs out of food, sulfur limitation drives its development from a unicellular to a multicellular organism. Researchers at the Max Planck Institute of Immunobiology and Epigenetics present the nutrient signaling pathways in this early eukaryote in great detail. Their results show how metabolism may have played a crucial...
by University of California – San Diego Researchers at University of California San Diego School of Medicine have discovered differences in brain circuitry that contribute to starvation and weight loss in people with anorexia nervosa (AN). The findings, published in the March 12, 2020 online issue of The American Journal of Psychiatry, shed new light...
