A new treatment which reboots the immune system using stem cell transplantation could relieve MS symptoms Multiple sclerosis (MS), a disease roughly 5,000 people are diagnosed with in the UK every year, is unpredictable and notoriously difficult to treat. That might all be about to change thanks to a breakthrough stem cell study that...
Tag: <span>Stem Cell therapy</span>
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Stem cell therapy may help reverse effects of premature menopause, restore fertility
Young women with premature ovarian insufficiency (POI) may be able to use their own bone marrow stem cells to rejuvenate their ovaries and avoid the effects of premature menopause, new research suggests. The preliminary results from the ongoing ROSE clinical trial will be presented Tuesday at ENDO 2018, the 100th annual meeting of the Endocrine Society, in...
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Stem cells pave the way for new treatment of diabetes
415 million people worldwide have been diagnosed with diabetes. And the number continues to rise. Common to all diabetes patients is that they lack the ability to produce sufficient amounts of insulin, which regulates the blood sugar in the body. This can lead to a number of complications and in many cases be potentially fatal....
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Generation of “Off-the-Shelf” Natural Killer Cells from Peripheral Blood Cell-Derived Induced Pluripotent Stem Cells
Highlights A GMP-compatible iPSC source has been generated from peripheral blood cells An industry-friendly protocol has been developed to produce NK cells from iPSCs These iPSC-derived NK cells are high-purity, functional, and KIR negative These iPSC-derived NK cells recognize and kill a wide variety of cancer cells Summary Current donor cell-dependent strategies can only produce...
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PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer’s Disease
Highlights PSEN1 mutant AD astrocytes manifest hallmarks of AD pathology Altered mitochondrial metabolism in AD astrocytes increases oxidative stress AD astrocytes reduce the calcium signaling activity of healthy neurons Astrocytes are important in the pathogenesis of AD Summary Alzheimer’s disease (AD) is a common neurodegenerative disorder and the leading cause of cognitive impairment. Due to insufficient...
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Type 1 diabetes: Could modified blood stem cells lead to a cure?
Increasing levels of a certain protein in blood stem cells so that the immune system stops attacking insulin cells in the pancreas could be a way to halt type 1 diabetes, according to a new study reported in Science Translational Medicine. Scientists may have devised a way to reverse type 1 diabetes. Researchers led by those...
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Stem Cell Therapy Shows Promise for Common Cause of Blindness
Two studies show cell-based treatment is safe in patients with dry macular degeneration, with one showing improved vision NEW ORLEANS, Nov. 14, 2017 /PRNewswire/ — Results from two early clinical trials show that it may be possible to use human embryonic stem cells as treatment for the dry form of macular degeneration, according to presentations given today at...
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Transplanted Hematopoietic Stem Cells Reverse Damage Caused by Neuro-muscular Disorder
Researchers at University of California San Diego School of Medicine report that a single infusion of wildtype hematopoietic stem and progenitor cells (HSPCs) into a mouse model of Friedreich’s ataxia (FA) measurably halted cellular damage caused by the degenerative disease. The findings, published online in the October 25 issue of Science Translational Medicine, suggest a potential...
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Cell Therapy
About Cell therapy Cell therapy is a new official direction in medicine, based on the use of regenerative potential of the adult stem cells, aimed at the treatment of a variety of serious diseases, rehabilitation of patients after injuries and fighting with the premature signs of aging. Stem cells are also considered to be the promising...
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Stem cell therapy for lung fibrosis conditions
A team of scientists from the UNC School of Medicine and North Carolina State University (NCSU) has developed promising research towards a possible stem cell treatment for several lung conditions, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and cystic fibrosis — often-fatal conditions that affect tens of millions of Americans. In...