Researchers have pinpointed a key enzyme that is vital for the production of fresh blood cells in the body. The enzyme is essential for the survival of specialised stem cells that give rise to new blood cells, the study found. Experts say the findings could help to improve the success of stem cell therapies that...
Tag: <span>Stem Cell therapy</span>
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Stem cell therapy holds promise for treating most severe cases of angina
An analysis of data from the entire development program consisting of three trials assessing the feasibility of using a stem cell therapy (CD34+ cells) to treat patients with the most severe cases of angina, refractory angina (RA), showed a statistically significant improvement in exercise time as well as a reduction in mortality. Results from “CD34+...
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It’s all in the math: New tool provides roadmap for cell development
Topological representation of four cellular populations during motor neuron differentiation. Researchers at Columbia University Medical Center have created a new tool to describe the many possible ways in which a cell may develop. Rooted in the mathematical field of topology, the tool provides a roadmap that offers detailed insight into how stem cells give rise...
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Discovery offers new hope to repair spinal cord injuries
Todd McDevitt (right), Jessica Butts (center) and Dylan McCreedy (left) created a special type of neuron from human stem cells that could potentially repair spinal cord injuries. Scientists at the Gladstone Institutes created a special type of neuron from human stem cells that could potentially repair spinal cord injuries. These cells, called V2a interneurons, transmit...
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Test run finds no cancer risk from stem cell therapy
A colony of induced pluripotent stem cells. Blue fluorescence indicates cell nuclei; red and green are markers of pluripotency. Therapeutic stem cells can be made without introducing genetic changes that could later lead to cancer, a study in PLOS Genetics has found. The discovery, made by researchers at the Wellcome Trust Sanger Institute, is a boost...
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Potential of stem cell therapy to repair lung damage
A new study has found that stem cell therapy can reduce lung inflammation in an animal model of chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Although, still at a pre-clinical stage, these findings have important potential implications for the future treatment of patients. The findings were presented in Estoril, Portugal today (25 March, 2017)...
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From skin to brain: Stem cells without genetic modification
The top four images, from left to right, show Keratinocyte-derived neural crest stem cells turning into neurons as shown by typical neuronal morphology. The larger image, directly above, is a close-up of the far right image. A discovery, several years in the making, by a University at Buffalo research team has demonstrated that adult skin...
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Mannitol-enhanced delivery of stem cells and their growth factors across the blood-brain barrier
Abstract Ischemic brain injury in adults and neonates is a significant clinical problem with limited therapeutic interventions. Currently, clinicians have only tPA available for stroke treatment and hypothermia for cerebral palsy. Owing to the lack of treatment options, there is a need for novel treatments such as stem cell therapy. Various stem cells including cells...
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Stem cell transplants offer hope for sufferers of gut disorders
Enteric neurosphere in mice. After a baby is born, a souvenir of its months in the womb is usually not long to follow. Its first poo, or meconium, is a lump sum of everything the foetus has ingested for months; a dark sludge, compared by the insomniac readers of parenting forums to engine oil...
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Study shows potential of stem cell therapy to repair lung damage
A new study has found that stem cell therapy can reduce lung inflammation in an animal model of chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Although, still at a pre-clinical stage, these findings have important potential implications for the future treatment of patients. The findings were presented in Estoril, Portugal on 25 March, 2017 at the European Respiratory Society’s...