Scientists working to develop more effective treatments for diabetes are turning to stem cells. Such cells can be transformed into cells that produce insulin, the hormone that controls blood sugar. But there’s a major challenge: the amount of insulin produced by theses cells is difficult to control. Researchers at Washington University School of Medicine in...
Tag: <span>Stem Cell</span>
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Flow of cerebrospinal fluid regulates neural stem cell division
Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory. In a paper published in the journal ‘Cell Stem Cell‘, scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München (LMU) have shown how this works. They found that ion channels play a key role in mediating force signals...
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Flow of cerebrospinal fluid regulates neural stem cell division
Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory. In a paper published in the journal ‘Cell Stem Cell‘, scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München (LMU) have shown how this works. They found that ion channels play a key role in mediating force signals...
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DNA methylation plays key role in stem cell differentiation
Neural progenitors cells differentiated from human embryonic stem cells. Northwestern Medicine scientists have discovered how the process of DNA methylation regulates the development of spinal cord motor neurons, according to a study published in the journal Cell Stem Cell. DNA methylation, an epigenetic mechanism that determines whether or not a gene is expressed, guides stem...
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Stem cell transplants are a ‘game changer’ for MS patients: Trial shows the pioneering method can stop the debilitating disease in its tracks
More than 100 patients with a common form of MS were involved in the study They were either given a stem cell transplant or were given conventional drugs The £30,000 treatment involves flooding the immune system with cancer drugs The immune system is then rebooted with stem cells from the MS patient’s blood Stem cell...
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Nanostructures created by UCLA scientists could make gene therapies safer, faster and more affordable
UCLA scientists have developed a new method that utilizes microscopic splinter-like structures called “nanospears” for the targeted delivery of biomolecules such as genes straight to patient cells. These magnetically guided nanostructures could enable gene therapies that are safer, faster and more cost-effective. The research was published in the journal ACS Nano by senior author Paul...
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Synthetic Stem Cells Could Offer Therapeutic Benefits, Reduced Risks
Researchers from North Carolina State University, the University of North Carolina at Chapel Hill and First Affiliated Hospital of Zhengzhou University have developed a synthetic version of a cardiac stem cell. These synthetic stem cells offer therapeutic benefits comparable to those from natural stem cells and could reduce some of the risks associated with stem...
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Researchers create skeletal muscle from stem cells
Skeletal muscle cells isolated using the ERBB3 and NGFR surface markers (right) restore human dystrophin (green) after transplantation significantly greater than previous methods (left). UCLA scientists have developed a new strategy to efficiently isolate, mature and transplant skeletal muscle cells created from human pluripotent stem cells, which can produce all cell types of the body....
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Suite of Monash papers shed light on decade-long stem cell mystery
A series of studies led by Monash University researcher Associate Professor Jose Polo have this week shed light on vital, yet previously unclear, aspects of cell reprogramming. Cell reprogramming, in which one type of cell can be turned into almost any other type cell in the human body, is revolutionising medicine. It gives scientists the...
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Researchers find lung stem cell, heal lung injury in mice
An image of an injured mouse lung partially regenerated by injected lung stem cells. The newly regenerated lung tissue is red, and the type-2 alveolar cells are green. Stanford scientists have found a cell that creates the two different compartments in the mouse lung. They hope their discovery could lead to better therapies for...