T cells (red) that were produced using artificial thymic organoids developed by UCLA scientists. UCLA researchers have created a new system to produce human T cells, the white blood cells that fight against disease-causing intruders in the body. The system could be utilized to engineer T cells to find and attack cancer cells, which...
Tag: <span>Stem Cell</span>
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Method identified to boost detection of highly cancerous stem cells
Cancer stem cells (CSCs) escape from 5-aminolevulinic acid (5-ALA)-based photodynamic detection (PDD) (upper panel). An iron chelator deferoxamine (DFO) enhances accumulation in CSCs of PpIX from 5-ALA, which will facilitate the elimination …more Japanese researchers identify process to improve fluorescence detection of cancer stem cells, which are primarily responsible for brain tumor progression and recurrence...
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The stem cell dynamics of wound healing
Researchers at the Université libre de Bruxelles, ULB define for the first time the changes in the stem cell dynamics that contribute to wound healing. One of the key questions in biology is to identify how tissues are repaired after trauma and understand how stem cells migrate, proliferate, and differentiate to repair tissue damage. In a study...
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Researchers engineer new thyroid cells
Researchers have discovered a new efficient way to generate thyroid cells, known as thyrocytes, using genetically modified embryonic stem cells. Researchers have discovered a new efficient way to generate thyroid cells, known as thyrocytes, using genetically modified embryonic stem cells. The findings, which appear in the journal Stem Cell Reports, are the first step to developing...
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Stem cells collected from fat may have use in anti-aging treatments
Adult stem cells collected directly from human fat are more stable than other cells — such as fibroblasts from the skin — and have the potential for use in anti-aging treatments, according to researchers from the Perelman School of Medicine at the University of Pennsylvania. They made the discovery after developing a new model to...
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Stem cell strategy for boosting testosterone levels tested in rodents
Male hypogonadism is a condition that diminishes testosterone levels in approximately 30% of older men, but currently available therapies can produce serious side effects. In a study published December 22 in Stem Cell Reports, researchers developed an alternative approach involving the direct conversion of adult skin cells into functional testosterone-producing cells. When transplanted into male rodents...
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New findings about stem cells in the brain of patients with epilepsy
Neural stem cells have been found in epileptic brain tissue — outside the regions of the brain where they normally reside. In a group of patients who underwent surgery for epilepsy, over half had stem cells where healthy individuals do not have them, according to a study from Sahlgrenska Academy. “We have confirmed what earlier...
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Lipid metabolism is potential ‘Achilles’ heel’ for cancer stem cells
WEST LAFAYETTE, Ind. — Researchers have discovered a metabolic signature critical for the functioning of “cancer stem cells” that initiate tumor formation. The team also showed how to interfere with this metabolic mechanism in ovarian cancer, inhibiting tumor growth. “The cancer stem cells are resistant to conventional therapies and are responsible for tumor relapse after...
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New method uses sound to see vividly inside living cells
A new nanoscale ultrasound technique for imaging live cells could rival the optical super-resolution techniques which won the 2014 Nobel Prize for Chemistry.(Credit: University of Nottingham) Researchers from The University of Nottingham (UN) have developed a groundbreaking technique that uses sound rather than light to see inside live cells. The new technique provides insight into the structure...
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Living Bandage: Researchers Trial New Stem Cell Therapy For Knee Injuries On Humans
A new treatment for meniscal tears based on stem cells has just been used for the first time on human subjects, with very encouraging results. The new method may help hundreds of thousands of sportsmen each year, easing their recovery and reducing the risk of developing other afflictions. A Widespread Problem Meniscal tears are some of the...