Tens of thousands of people each year are left paralysed to some degree by a stroke. Billy Elder, 63, from Renfrew, Glasgow, is one of the first people to receive a new stem cell treatment to restore movement, as he tells OONA MASHTA . . THE PATIENT One day in August last year I was...
Tag: <span>Stem Cell</span>
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Study investigates how to turn stem cells into motor neurons
Stem cells can develop into many different types of cells, such as muscle cells, red blood cells, or neurons. Given their special regenerative ability, stem cells can be used to treat a wide range of diseases. A team of researchers uncovers new details involved in the process of turning stem cells into motor neurons....
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Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas
Highlights Sumoylation regulates CD44 and MMP14 expression in basal breast and colon cancer SUMO inhibition clears cancer stem cells, repressing invasiveness and tumor growth Anacardic acid functions as a SUMO inhibitor to repress cancer stem cells TFAP2A mediates anti-tumor effects of SUMO inhibition in breast and colon cancers Summary Many solid cancers have an expanded...
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Direct Conversion of Human Fibroblasts into Neural Progenitors Using Transcription Factors Enriched in Human ESC-Derived Neural Progenitors
Highlights iENPs can be converted from fibroblasts using hESC-ENP enriched factors iENPs exhibit cellular and molecular characteristics resembling hESC-ENPs iENPs induced by different TF combinations exhibit different neural propensity iENP and their neuronal derivatives recapitulated HD and AD phenotypes Summary Early human embryonic stem cell (hESC)-derived neural populations consist of various embryonic neural progenitors (ENPs)...