JUNE 24, 2024 by University of Copenhagen Credit: Cell (2024). DOI: 10.1016/j.cell.2024.05.051An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen. The paper, titled “The primitive endoderm supports linage plasticity to enable regulative development,” was...
JUNE 11, 2024 by National Comprehensive Cancer Network Credit: CC0 Public Domain New research in the June 2024 issue of Journal of the National Comprehensive Cancer Network highlights a promising approach for alleviating distress, enhancing quality of life, improving physical function, and reducing fatigue in patients with blood cancers who undergo hematopoietic stem cell transplantation...
By MAIYA FOCHT FOR DAILYMAIL.COM PUBLISHED: 07:31 EDT, 1 June 2024 | UPDATED: 07:51 EDT, 1 June 2024 When Robin Gordon-Cartier was first diagnosed with multiple sclerosis at 50 years old she felt like she was ‘just waiting to die.’ Her busy life as a harpist, full-time teacher and travelling performer was slowly eroding because...
JUNE 3, 2024 by Karolinska Institutet a, Left, experimental design (partly created with Biorender.com) for single-cell RNA sequencing of HSPCs generated by single Vwf-tdTomato+ P-HSCs (n = 7) or Vwf-tdTomato− multi-HSCs. Right, mean (dots indicate individual mice) contribution to blood lineages. b, UMAP of LIN−cKIT+ cells replenished by single Vwf-tdTomato+ P-HSCs (blue; n = 7 mice, 2,290 cells) or...
MAXIMUM ACADEMIC PRESS IMAGE: SCHEMATIC REPRESENTATION OF THE THERAPEUTIC EFFECT OF HYBMSC-EXOS ON DIABETIC WOUNDS. view moreCREDIT: BURNS & TRAUMA Researchers unveiled a novel therapy for diabetic wound healing. This research highlights the use of exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells (BMSCs) to significantly enhance wound healing by promoting keratinocyte autophagy. Diabetic...
KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY (KAUST) IMAGE: RESEARCHERS HAVE IDENTIFIED A METHOD TO ENHANCE THE REGENERATIVE CAPABILITIES OF STEM CELLS FOUND IN UMBILICAL CORD BLOOD, WHICH COULD HAVE BENEFITS FOR BONE MARROW TRANSPLANTS. view moreCREDIT: © 2024 KAUST; HENO HWANG. A method that enhances the functionality of an often-overlooked type of stem cell...
Ted Bosworth West Palm Beach, Florida — In an interim analysis of an extension study, intrathecal injection of autologous bone marrow–derived mesenchymal stem cells (MSCs) has been associated with favorable effects on both symptoms and biomarkers in patients with progressive multiple sclerosis (MS), new data presented as a late breaker at the annual meeting held...
by City of Hope National Medical Center Type II interferon (IFNy), a substance produced by immune cells, disrupts the leukemia stem cells’ ability to divide and spread cancer. However, IFNy also stimulates CD38, a protein that suppresses the immune cells’ ability to mount a response against infection. To overcome this challenge, City of Hope researchers designed...
Researchers say the genetically engineered stem cells also could pave the way for new regenerative medicine treatments for diseases such as Type 1 diabetes. Deepta Bhattacharya, who is on the University of Arizona Health Sciences Center for Advanced Molecular and Immunological Therapies advisory council, is a professor of immunobiology in the UArizona College of Medicine...
by University of California, Irvine Credit: Molecular Cell (2023). DOI: 10.1016/j.molcel.2023.10.036 Researchers at the University of California, Irvine, discovered a mechanism that controls the identity of stem cells. When this mechanism fails, embryonic stem cells revert back in time and become totipotent. When a cell becomes totipotent, this rare change enables the cells to differentiate into...
