Tag: <span>Stem Cells</span>

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Potential biomarker identified to screen quality of donor’s stem cells before harvesting

Durham, NC – A new study released today in STEM CELLS addresses a significant problem that has been confronting human mesenchymal stem cells (hMSCs) therapy. While hundreds of clinical trials involving thousands of patients are under way to test hMSCs’ ability to treat everything from heart disease to brain injury, there has been no way...

Intranasal delivery of MSCs provides hope for treating Alzheimer’s disease
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Intranasal delivery of MSCs provides hope for treating Alzheimer’s disease

Durham, NC – In the search for a cure for Alzheimer’s disease, mesenchymal stem cells and their derived extracellular vesicles (MSC-EVs) offer much promise, thanks to their protective and anti-inflammatory properties. The results from a new study done on mice, released today in STEM CELLS Translational Medicine, strengthens this idea by showing for the first...

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Caveolin binding motif in Na/K-ATPase required for stem cell differentiation in animals

HUNTINGTON, W.Va. – New findings reveal the importance of the Na/K-ATPase protein in stem cell differentiation and organogenesis, in a study led by scientists at Marshall University that involves the scaffolding function of the Na/K-ATPase. The research, published today in Science Advances, indicates that a sequence in the Na/K-ATPase, also known as the sodium pump,...

Stem cell topical solution for baldness offers positive trial results
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Stem cell topical solution for baldness offers positive trial results

By Rich Haridy May 18, 2020 South Korean researchers have shown a stem-cell-based topical solution can regrow hair in both male and female subjects with common pattern baldness. The small, randomized, placebo-controlled trial found the treatment both safe and effective, with larger trials hoped to validate the results in more diverse populations. The most common...

Scientists create first roadmap of human skeletal muscle development
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Scientists create first roadmap of human skeletal muscle development

by University of California, Los Angeles An interdisciplinary team of researchers at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at UCLA has developed a first-of-its-kind roadmap of how human skeletal muscle develops, including the formation of muscle stem cells. The study, published in the peer-reviewed journal Cell Stem Cell,...

Scientists generate millions of naïve human pluripotent stem cells, far more than have ever been produced
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Scientists generate millions of naïve human pluripotent stem cells, far more than have ever been produced

For decades, the enormous disease-curing potential of human stem cells has been thwarted by the inability to produce sufficient quantities of mature human cells in vivo — in a living organism. Now, a team led by University at Buffalo scientists has developed a method that dramatically ramps up the production of mature human cells in...

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New research into stem cell mutations could improve regenerative medicine

New research from the University of Sheffield into stem cells could help make regenerative medicine safer Regenerative medicine involves using pluripotent stem cells to repair damaged or diseased tissues in the body The new research has suggested ways to reduce the likelihood of mutations occurring in these cells when cultured. Research from the University of...

Mice with patchy coats lay bare how stem cells endure
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Mice with patchy coats lay bare how stem cells endure

Whether we like it or not, our hair continually grows. Its regenerative powers reside deep inside each hair follicle, in a cluster of dividing stem cells—some of which will specialize and eventually give rise to new hair while others will produce new stem cells. Scientists have delineated numerous mechanisms that guide stem cells toward particular...