The self-eating process in embryonic stem cells known as chaperone-mediated autophagy (CMA) and a related metabolite may serve as promising new therapeutic targets to repair or regenerate damaged cells and organs, Penn Medicine researchers show in a new study published online in Science. Human bodies contain over 200 different types of specialized cells. All of...
Tag: <span>Stem Cells</span>
Adult stem cells/glaucoma drug combo promotes diabetic wound healing in mice
ALPHAMED PRESS A BIOENGINEERED SCAFFOLD CONTAINING HYPOXIA-PRECONDITIONED, ALLOGENEIC HUMAN MSCS COMBINED WITH A BETA-ADRENERGIC ANTAGONIST, TIMOLOL, TO TREAT DIABETIC WOUNDS IN MICE. THE OPTIMIZED TREATMENT IMPROVED RE-EPITHELIALIZATION BY 65.6% WITH THE… view more CREDIT: ALPHAMED PRESS Durham, NC – A new study released today in STEM CELLS Translational Medicine shows promise of a major breakthrough...
2 immunotherapies merged into single, more effective treatment
Mouse study suggests strategy may work against variety of cancers WASHINGTON UNIVERSITY SCHOOL OF MEDICINE RESEARCHERS AT WASHINGTON UNIVERSITY SCHOOL OF MEDICINE IN ST. LOUIS HAVE COMBINED TWO TYPES OF IMMUNOTHERAPY INTO A SINGLE TREATMENT THAT MAY BE MORE EFFECTIVE AND POSSIBLY SAFER THAN CURRENT… view more CREDIT: JULIA WAGNER Some of the most promising...
A never-before-seen cell state may explain cancer’s ability to resist drugs
MEMORIAL SLOAN KETTERING CANCER CENTER Cancer’s knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back. Scientists once thought that unique genetic mutations in tumors underlay this drug resistance. But more and more, they...
New platform enables long-term tracking of stem cell-derived tissues after transplantation
ALPHAMED PRESS CO-AUTHORS SO GUN HONG, DVM, PH.D., AND CYNTHIA DUNBAR, M.D., OF THE NATIONAL HEART, LUNG, AND BLOOD INSTITUTE (NHLBI), PART OF THE NATIONAL INSTITUTES OF HEALTH.view more CREDIT: ALPHAMED PRESS Durham, NC – A new platform reported on today in STEM CELLS Translational Medicine (SCTM) will enable long-term tracking of cardiomyocytes produced from...
How to repair your gut
MONASH UNIVERSITY FLUORESCENT PICTURE OF AN INTESTINAL ORGANOID (STAINED FOR THE PROLIFERATION MARKER KI-67 (WHITE), THE STEM CELL MARKER EPHB2 (RED) AND DNA (BLUE). view more CREDIT: (C) MONASH BDI In a world first, Monash University researchers have identified a key biomolecule that enhances the repair of your gut lining by prompting stem cells to...
Turning off “junk DNA” may free stem cells to become neurons
For every cell in the body there comes a time when it must decide what it wants to do for the rest of its life. In an article published in the journal PNAS, National Institutes of Health researchers report for the first time that ancient viral genes that were once considered “junk DNA” may play...
Bone disease medications may reverse hearing loss
by Ryan Jaslow, Harvard Medical School Preliminary findings from Harvard Medical School researchers at Massachusetts Eye and Ear may pave the way for trials to test bone density medications for hearing loss. Hearing loss caused by damaged nerves, whether from sound exposure or aging, is irreversible. There are currently no medications approved by the Food...
Stem Cell Exhaustion in the Aging Lung
Stem cell activity declines with age throughout the body. In some cases this is because stem cellsbecome less active in response to changes in the signaling environment. In other cases, the cells are damaged or the populations greatly reduced. The consequence of this decline is that fewer daughter somatic cells are produced to make up...
Liposuction treatment hope for coronavirus: Stem cells taken from fat-reduction donors boosts survival rates FIVE-fold for critically-ill patients hooked up to ventilators
By VANESSA CHALMERS HEALTH REPORTER FOR MAILONLINE PUBLISHED: 13:41 EDT, 10 July 2020 | UPDATED: 13:54 EDT, 10 July 2020 Of a small number of patients, 15% died compared with the 85% expected Overall 70% of patients who were on the brink of death saw improvements The researchers admitted they did not expect such positive...