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Discovery: New biomarker for cancer stem cells

Protein linked to tumor survival and spread UNIVERSITY OF HOUSTON In the world of cancer biology, not all biomarkers are created equal. These molecules that alert doctors that an abnormal process may be underway can appear as an array of aberrant proteins, such as hormones, enzymes or signaling molecules, and vary from patient to patient....

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High-tech foam offers new tool for developing stem cells

Two Florida State University researchers are developing a high-tech material currently used in athletic equipment and prosthetics into a special tool to better develop stem cells. The work could improve drug screening, disease modeling, precision medicine, and cell therapy. FAMU-FSU College of Engineering researchers Yan Li, an associate professor in chemical and biomedical engineering, and...

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Stem cell transplants used to grow fully functional lungs in mice

by Columbia University Irving Medical Center Researchers at Columbia University were able to grow fully functional lungs in mouse embryos using transplanted stem cells. The findings suggest that it may be ultimately possible to use the technique to grow human lungs in animals for patients who need transplants and to study new lung treatments. The...

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How Stem Cells Make Decisions

Posted Today This news or article is intended for readers with certain scientific or professional knowledge in the field. Pluripotency is a feature of stem cell populations in which individual cells must know a great deal about their surroundings. If you’re a human embryonic stem cell — and who among us hasn’t been — the G1 (“Gap 1”) phase of development is...

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When added to gene therapy, plant-based compound may enable faster, more effective treatments

Scripps Research team finds that a nontoxic molecule closely related to resveratrol can overcome barriers to delivering gene therapy into stem cells. SCRIPPS RESEARCH INSTITUTE LA JOLLA, CA – Gene therapy has broadened the treatment possibilities for those with immune system deficiencies and blood-based conditions, such as sickle cell anemia and leukemia. These diseases, which...

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New mechanisms that regulate pluripotency in embryonic stem cells are discovered

by Karina Toledo, FAPESP Embryonic stem cells (ESCs) can give rise to many types of tissues and organs. At the turn of the century, these cells were believed to offer hope of treatment for several health problems, but as research advanced, scientists realized that understanding and controlling the behavior of ESCs would be a more...

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Woman is first to receive cornea made from ‘reprogrammed’ stem cells

The Japanese woman’s vision has improved since the transplant, say her doctors. At a press conference on 29 August, ophthalmologist Kohji Nishida from Osaka University, Japan, said the woman has a disease in which the stem cells that repair the cornea, a transparent layer that covers and protects the eye, are lost. The condition makes vision blurry and can lead to blindness....

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Can Stem Cells be Used to Treat Epilepsy?

By Osman Shabir, M.Sc. Reviewed by Dr. Jennifer Logan, MD, MPH Epilepsy is a neurological condition characterized by recurrent episodes of seizures. Most cases of epilepsy do not have a clear known cause, apart from susceptible genetic factors. The primary pathogenesis of genetic forms of epilepsy is an abnormal expression of certain receptors in the brain that lead to...

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Decoding Cells to Unlock Stem Cells’ Potential

Posted Today Stem cells are jacks of all trades, capable of alleviating the consequences of such diverse pathologies as heart attacks, strokes and cancer. However, stem cell therapies have been hampered by possible side effects, which are frequently hard to predict. One way around this conundrum is to understand how stem cells conjure up their therapeutic...

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