Randy Dotinga September 13, 2023 In a new salvo in the dispute over the wisdom of early “bridging” treatment with glucocorticoids in rheumatoid arthritis, Dutch researchers suggested in a new meta-analysis that the American College of Rheumatology guideline is too cautious. The report, published in Annals of the Rheumatic Diseases, examined three randomized trials of...
by University of Edinburgh Credit: Pixabay/CC0 Public Domain Women who experience heavy menstrual bleeding could have their blood loss reduced by treatment with a common anti-inflammatory steroid, research suggests. The study could pave the way for dexamethasone to be used as a safe, effective therapy—the first new class of treatment for heavy menstrual bleeding in nearly 20 years. It is the...
Single ALLO injection during pregnancy was enough to avert both the cerebellar abnormalities and the aberrant social behaviors in experimental models CHILDREN’S NATIONAL HOSPITAL CHICAGO-A study in experimental models suggests that allopregnanolone, one of many hormones produced by the placenta during pregnancy, is so essential to normal fetal brain development that when provision of that...
Steroids act on adipocyte glucocorticoid receptors (GRs) :Activation of adipocyte GRs restricted healthy adipose expansion, causing insulin resistance, liver steatosis, and eventually diabetes. Credit: Osaka University Steroids are used for treating various diseases such as allergic disorders, but they occasionally cause adverse effects, such as steroid diabetes and other metabolic disturbances. Since steroids act throughout...
