Tag: <span>STING</span>

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What is a STING antagonist?
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What is a STING antagonist?

By Michael Greenwood, M.Sc. Reviewed by Sophia Coveney, B.Sc. Stimulators of interferon genes (STING) are cytosolic sensors associated with the endoplasmic reticulum that respond to the presence of dsDNA in the cytosol, usually indicative of an invading pathogen or self-leaked DNA from damaging events. Image Credit: Christoph Burgstedt/Shutterstock.com Cytoplasmic DNA is firstly bound with the...

Can scientists take the STING out of common respiratory viruses?
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Can scientists take the STING out of common respiratory viruses?

by  University of North Carolina at Chapel Hill School of Medicine University of North Carolina School of Medicine scientists have made a curious discovery about a well-known human protein that helps the immune system fight viral infections. The lab of Stan Lemon MD, and colleagues found that one class of viruses actually requires this protein to...