by Okinawa Institute of Science and Technology When encapsidated in budding HIV-1 virions, APOBEC3G (A3G) suppresses viral amplification by modifying the viral genome after reverse transcription in infected cells (left). But HIV-1 Vif catalyzes degradation of A3G, leading to infectious virions (right). Credit: OIST The HIV-1 virus can neutralize cellular defenses with its viral infectivity factor...
Tag: <span>structure</span>
New technology enables the manufacture of materials that mimic the structure of living blood vessels
by University of Sydney Artist’s representation of the ‘living blood vessel’. Credit: Ziyu Wang, Ella Maru Studio An international consortium of researchers led by the University of Sydney, has developed technology to enable the manufacturing of materials that mimic the structure of living blood vessels, with significant implications for the future of surgery. Preclinical testing...
DeepMind found the structure of nearly every protein known to science
By Nicole Wetsman Jul 28, 2022, 7:00am EDT A protein structure identified by AlphaFold. Image: DeepMind DeepMind is releasing a free expanded database with its predictions of the structure of nearly every protein known to science, the company, a subsidiary of Google parent Alphabet, announced today. DeepMind transformed science in 2020 with its AlphaFold AI software, which produces highly accurate...
Prion diseases: New clues in the structure of prion proteins
by International School of Advanced Studies (SISSA) Photomicrograph of a neural tissue specimen, harvested from a scrapie affected mouse, revealing the presence of prion protein stained in red. Credit: National Institute of Allergy and Infectious Diseases(NIAID) Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals. Bovine spongiform...