Tag: <span>super-enhancers</span>

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Super-enhancers: The villain fueling certain cancers
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Super-enhancers: The villain fueling certain cancers

IMAGE: (A) WESTERN BLOT ANALYSIS OF MYC IN INDICATED CELL LINES AFTER TRANSFECTION WITH 10 NMOL/L OF MIR-NC OR MIR-766-5P. THE INTENSITY OF MYC BANDS WAS QUANTIFIED BY DENSITOMETRY AND SHOWN AS THE FOLD CHANGE AFTER NORMALIZATION WITH Β-ACTIN. NA, NOT APPLICABLE. (B) WESTERN BLOT ANALYSIS OF CBP AND BRD4 IN HCT116-/- CELLS 48 HOURS...

Biologists discover super-enhancers that switch on breast cancer genes
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Biologists discover super-enhancers that switch on breast cancer genes

by City University of Hong Kong  CityU Researcher (Hu Jianyang) displays the microscopic image of the 3D breast cancer cell line derived from a patient’s tumor. Credit: City University of Hong Kong Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option,...