A new synthetic antibiotic developed by University of Liverpool researchers is shown to be more effective than established drugs against ‘superbugs’ such as MRSA, a new study shows.New synthetic antibiotic in action – artistic interpretation. Image credit: University of Liverpool The study demonstrates the potent activity of the antibiotic, teixobactin, against bacterial biofilms. Biofilms are...
Tag: <span>synthetic antibiotic</span>
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A broad-spectrum synthetic antibiotic that does not evoke bacterial resistance
by Shelly Leachman, University of California – Santa Barbara Conjugated oligoelectrolytes (COEs) and comparative bactericidal activity and mammalian cell cytotoxicity. a, COEs share a modular structure that spontaneously integrates into the bacterial membrane. b and c, COE structural modules are depicted by colored boxes. The intercalation into phospholipid bilayers is driven by the hydrophobic center...
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Florida International University researchers patent synthetic antibiotic
FLORIDA INTERNATIONAL UNIVERSITY COLLEGE OF MEDICINE IMAGE: MASAFUMI YOSHINAGA, PH.D., BARRY P. ROSEN, PH.D., STANISLAW WNUK, PH.D., AND THE CHEMICAL FORMULA FOR ARSINOTHRICIN. CREDIT: FLORIDA INTERNATIONAL UNIVERSITY Florida International University researchers have moved a step closer to producing synthetic arsenic-based drugs in their quest to solve an urgent worldwide health problem ―the growing number of...
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A synthetic antibiotic may help turn the tide against drug-resistant pathogens
by Rockefeller University Credit: CC0 Public Domain A new antibiotic, synthesized at The Rockefeller University and derived from computer models of bacterial gene products appears to neutralize even drug-resistant bacteria. The compound, named cilagicin, works well in mice and employs a novel mechanism to attack MRSA, C. diff, and several other deadly pathogens, according to...
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Customizable synthetic antibiotic outmaneuvers resistant bacteria
UNIVERSITY OF CALIFORNIA – SAN FRANCISCO Antibiotic resistance is one of the world’s most urgent public health threats. In the United States alone, tens of thousands of deaths result each year from drug-resistant strains of common bacteria such as Staphylococcus aureus and Enterococcus faecium, which can cause virtually untreatable hospital-acquired infections. Perilously few new classes...